Statistical Assessment of Chromatographic Response Functions vs. Solvent Mixture Model
a₁x₁+a₂x₂+a₃x₃+a₄x₁x₂+a₅x₁x₃+a₆x₂x₃+a₇x₁x₂x₃

RF	X1	X2	X3	L	C1	C2	C3	C4	C5
0	1	1	1	8.70	0.764	0.845	0.834	0.460	0.547
1	0	0	1	8.83	0.000	0.000	0.000	0.000	0.000
2	0	1	0	8.75	0.947	0.970	0.970	0.906	0.890
3	1	0	0	9.00	0.134	0.228	0.159	0.006	0.021
4	1	0	1	8.93	0.060	0.110	0.076	0.000	0.000
5	1	1	0	8.84	0.759	0.805	0.798	0.601	0.629
6	0	1	1	8.76	0.963	0.977	0.977	0.839	0.822
7	1	1	8	8.86	0.394	0.532	0.509	0.060	0.072
8	8	1	1	8.87	0.573	0.756	0.683	0.114	0.262
9	1	8	1	8.82	0.934	0.954	0.959	0.837	0.824
10	55	19	26	18.95	0.181	0.309	0.608	0.709	0.759

RFE	C1	C2	C3	C4	C5
0	0.764	0.845	0.834	0.460	0.547
1	0.000	0.000	0.000	0.000	0.000
2	0.947	0.970	0.970	0.906	0.890
3	0.134	0.228	0.159	0.006	0.021
4	0.060	0.110	0.076	0.000	0.000
5	0.759	0.805	0.798	0.601	0.629
6	0.963	0.977	0.977	0.839	0.822
7	0.291	0.314	0.308	0.203	0.216
8	0.309	0.393	0.347	0.139	0.174
9	1.017	1.052	1.053	0.878	0.891
10	0.505	0.591	0.565	0.253	0.324

No	Est	Exp
1	0.291	0.394
2	0.314	0.532
3	0.308	0.509
4	0.203	0.060
5	0.216	0.072
6	0.309	0.573
7	0.393	0.756
8	0.347	0.683
9	0.139	0.114
10	0.174	0.262
11	1.017	0.934
12	1.052	0.954
13	1.053	0.959
14	0.878	0.837
15	0.891	0.824
16	0.505	0.181
17	0.591	0.309
18	0.565	0.608
19	0.253	0.709
20	0.324	0.759

RSM	X1	X2	X3	L	C1-C2	C1-C3	C1-C4	C1-C5	C2-C3	C2-C4	C2-C5	C3-C4	C3-C5	C4-C5
0	1	1	1	8.70	1.687	1.718	6.163	2.589	0.310	9.178	3.895	10.689	4.132	1.118
1	0	0	1	8.83	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
2	0	1	0	8.75	0.635	0.833	1.108	1.042	0.000	2.074	1.647	2.872	2.000	0.322
3	1	0	0	9.00	1.570	0.427	2.729	2.217	1.442	5.882	4.960	4.312	3.493	0.528
4	1	0	1	8.93	0.936	0.337	1.317	1.333	0.923	3.062	3.111	2.566	2.615	0.000
5	1	1	0	8.84	0.953	0.907	3.077	1.855	0.275	5.403	3.120	6.214	3.348	0.476
6	0	1	1	8.76	0.511	0.585	3.254	1.425	0.000	5.762	1.826	6.722	1.902	0.178
7	1	1	8	8.86	2.392	2.318	6.805	2.836	0.571	12.116	4.448	14.473	4.580	0.131
8	8	1	1	8.87	2.717	1.903	8.059	4.182	1.529	13.735	7.702	15.303	7.711	2.758
9	1	8	1	8.82	0.447	0.667	2.048	1.311	0.263	3.679	1.900	4.696	2.164	0.172
10	55	19	26	18.95	2.455	7.191	9.671	10.234	4.371	6.290	6.871	1.433	2.080	0.732

RSME	C1-C2	C1-C3	C1-C4	C1-C5	C2-C3	C2-C4	C2-C5	C3-C4	C3-C5	C4-C5
0	1.687	1.718	6.163	2.589	0.310	9.178	3.895	10.689	4.132	1.118
1	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
2	0.635	0.833	1.108	1.042	0.000	2.074	1.647	2.872	2.000	0.322
3	1.570	0.427	2.729	2.217	1.442	5.882	4.960	4.312	3.493	0.528
4	0.936	0.337	1.317	1.333	0.923	3.062	3.111	2.566	2.615	0.000
5	0.953	0.907	3.077	1.855	0.275	5.403	3.120	6.214	3.348	0.476
6	0.511	0.585	3.254	1.425	0.000	5.762	1.826	6.722	1.902	0.178
7	0.512	0.456	1.968	0.891	0.178	3.211	1.402	3.639	1.409	0.207
8	1.515	0.786	3.447	2.253	1.062	6.404	4.542	5.912	3.770	0.586
9	0.872	1.082	3.081	1.620	-0.004	5.028	2.327	6.269	2.734	0.521
10	1.681	1.380	5.042	2.480	0.677	7.970	4.292	8.665	4.142	0.901

No	Est	Exp
1	0.512	2.392
2	0.456	2.318
3	1.968	6.805
4	0.891	2.836
5	0.178	0.571
6	3.211	12.116
7	1.402	4.448
8	3.639	14.473
9	1.409	4.580
10	0.207	0.131
11	1.515	2.717
12	0.786	1.903
13	3.447	8.059
14	2.253	4.182
15	1.062	1.529
16	6.404	13.735
17	4.542	7.702
18	5.912	15.303
19	3.770	7.711
20	0.586	2.758
21	0.872	0.447
22	1.082	0.667
23	3.081	2.048
24	1.620	1.311
25	-0.004	0.263
26	5.028	3.679
27	2.327	1.900
28	6.269	4.696
29	2.734	2.164
30	0.521	0.172
31	1.681	2.455
32	1.380	7.191
33	5.042	9.671
34	2.480	10.234
35	0.677	4.371
36	7.970	6.290
37	4.292	6.871
38	8.665	1.433
39	4.142	2.080
40	0.901	0.732

RFO	X1	X2	X3	L	SP5	SP6	SP7	SP8	SP9
0	1	1	1	8.70	0.460	0.547	0.764	0.834	0.845
1	0	0	1	8.83	0.000	0.000	0.000	0.000	0.000
2	0	1	0	8.75	0.890	0.906	0.947	0.970	0.970
3	1	0	0	9.00	0.006	0.021	0.134	0.159	0.228
4	1	0	1	8.93	0.000	0.000	0.060	0.076	0.110
5	1	1	0	8.84	0.601	0.629	0.759	0.798	0.805
6	0	1	1	8.76	0.822	0.839	0.963	0.977	0.977
7	1	1	8	8.86	0.060	0.072	0.394	0.509	0.532
8	8	1	1	8.87	0.114	0.262	0.573	0.683	0.756
9	1	8	1	8.82	0.824	0.837	0.934	0.954	0.959
10	55	19	26	18.95	0.181	0.309	0.608	0.709	0.759

RFOE	SP5	SP6	SP7	SP8	SP9
0	0.460	0.547	0.764	0.834	0.845
1	0.000	0.000	0.000	0.000	0.000
2	0.890	0.906	0.947	0.970	0.970
3	0.006	0.021	0.134	0.159	0.228
4	0.000	0.000	0.060	0.076	0.110
5	0.601	0.629	0.759	0.798	0.805
6	0.822	0.839	0.963	0.977	0.977
7	0.200	0.219	0.291	0.308	0.314
8	0.141	0.172	0.309	0.347	0.393
9	0.866	0.902	1.017	1.053	1.052
10	0.256	0.321	0.505	0.565	0.591

No	Est	Exp
1	0.200	0.060
2	0.219	0.072
3	0.291	0.394
4	0.308	0.509
5	0.314	0.532
6	0.141	0.114
7	0.172	0.262
8	0.309	0.573
9	0.347	0.683
10	0.393	0.756
11	0.866	0.824
12	0.902	0.837
13	1.017	0.934
14	1.053	0.954
15	1.052	0.959
16	0.256	0.181
17	0.321	0.309
18	0.505	0.608
19	0.565	0.709
20	0.591	0.759

RFD	X1	X2	X3	L	RFOdif
0	1	1	1	8.70	0.047
1	0	0	1	8.83	0.283
2	0	1	0	8.75	0.081
3	1	0	0	9.00	0.055
4	1	0	1	8.93	0.078
5	1	1	0	8.84	0.057
6	0	1	1	8.76	0.097
7	1	1	8	8.86	0.067
8	8	1	1	8.87	0.036
9	1	8	1	8.82	0.076
10	55	19	26	18.95	0.040

RFDE	RFOdif
0	0.047
1	0.283
2	0.081
3	0.055
4	0.078
5	0.057
6	0.097
7	0.181
8	0.042
9	0.062
10	0.039

No	Est	Exp
1	0.181	0.067
2	0.042	0.036
3	0.062	0.076
4	0.039	0.040

RSR	X1	X2	X3	L	RSreu
0	1	1	1	8.70	1.285
1	0	0	1	8.83	0.000
2	0	1	0	8.75	0.401
3	1	0	0	9.00	1.035
4	1	0	1	8.93	0.452
5	1	1	0	8.84	0.778
6	0	1	1	8.76	0.559
7	1	1	8	8.86	1.169
8	8	1	1	8.87	2.498
9	1	8	1	8.82	0.573
10	55	19	26	18.95	2.038

RSRE	RSreu
0	1.285
1	0.000
2	0.401
3	1.035
4	0.452
5	0.778
6	0.559
7	0.380
8	1.021
9	0.696
10	1.180

No	Est	Exp
1	0.380	1.169
2	1.021	2.498
3	0.696	0.573
4	1.180	2.038

QF	X1	X2	X3	L	RSmin
0	1	1	1	8.70	0.310
1	0	0	1	8.83	0.000
2	0	1	0	8.75	0.000
3	1	0	0	9.00	0.427
4	1	0	1	8.93	0.000
5	1	1	0	8.84	0.275
6	0	1	1	8.76	0.000
7	1	1	8	8.86	0.131
8	8	1	1	8.87	1.529
9	1	8	1	8.82	0.172
10	55	19	26	18.95	0.732

QFE	RSmin
0	0.310
1	0.000
2	0.000
3	0.427
4	0.000
5	0.275
6	0.000
7	0.028
8	0.344
9	0.105
10	0.311

No	Est	Exp
1	0.028	0.131
2	0.344	1.529
3	0.105	0.172
4	0.311	0.732

RSO	X1	X2	X3	L	RS5	RS6	RS7	RS8
0	1	1	1	8.70	1.118	2.589	1.718	0.310
1	0	0	1	8.83	0.000	0.000	0.000	0.000
2	0	1	0	8.75	0.322	1.108	0.833	0.000
3	1	0	0	9.00	0.528	2.217	0.427	1.442
4	1	0	1	8.93	0.000	1.317	0.337	0.923
5	1	1	0	8.84	0.476	1.855	0.907	0.275
6	0	1	1	8.76	0.178	3.254	0.585	0.000
7	1	1	8	8.86	0.131	2.836	2.318	0.571
8	8	1	1	8.87	2.758	4.182	1.903	1.529
9	1	8	1	8.82	0.172	2.048	0.447	0.263
10	55	19	26	18.95	2.455	4.371	1.433	0.732

RSOE	RS5	RS6	RS7	RS8
0	1.118	2.589	1.718	0.310
1	0.000	0.000	0.000	0.000
2	0.322	1.108	0.833	0.000
3	0.528	2.217	0.427	1.442
4	0.000	1.317	0.337	0.923
5	0.476	1.855	0.907	0.275
6	0.178	3.254	0.585	0.000
7	0.207	1.293	0.456	0.178
8	0.586	2.143	0.786	1.062
9	0.521	2.064	1.082	-0.004
10	0.901	2.238	1.380	0.677

No	Est	Exp
1	0.207	0.131
2	1.293	2.836
3	0.456	2.318
4	0.178	0.571
5	0.586	2.758
6	2.143	4.182
7	0.786	1.903
8	1.062	1.529
9	0.521	0.172
10	2.064	2.048
11	1.082	0.447
12	-0.004	0.263
13	0.901	2.455
14	2.238	4.371
15	1.380	1.433
16	0.677	0.732

DCN	X1	X2	X3	L	DCcnt
0	1	1	1	8.70	5
1	0	0	1	8.83	1
2	0	1	0	8.75	4
3	1	0	0	9.00	5
4	1	0	1	8.93	4
5	1	1	0	8.84	5
6	0	1	1	8.76	3
7	1	1	8	8.86	4
8	8	1	1	8.87	5
9	1	8	1	8.82	4
10	55	19	26	18.95	5

DCNE	DCcnt
0	5.000
1	1.000
2	4.000
3	5.000
4	4.000
5	5.000
6	3.000
7	2.368
8	5.168
9	4.328
10	5.220

No	Est	Exp
1	2.368	4
2	5.168	5
3	4.328	4
4	5.220	5

RSA	X1	X2	X3	L	RSavg
0	1	1	1	8.70	1.434
1	0	0	1	8.83	0.000
2	0	1	0	8.75	0.566
3	1	0	0	9.00	1.153
4	1	0	1	8.93	0.644
5	1	1	0	8.84	0.878
6	0	1	1	8.76	1.004
7	1	1	8	8.86	1.464
8	8	1	1	8.87	2.593
9	1	8	1	8.82	0.733
10	55	19	26	18.95	2.248

RSAE	RSavg
0	1.434
1	0.000
2	0.566
3	1.153
4	0.644
5	0.878
6	1.004
7	0.533
8	1.144
9	0.916
10	1.299

No	Est	Exp
1	0.533	1.464
2	1.144	2.593
3	0.916	0.733
4	1.299	2.248

RSS	X1	X2	X3	L	RSsum
0	1	1	1	8.70	5.73
1	0	0	1	8.83	0.00
2	0	1	0	8.75	2.26
3	1	0	0	9.00	4.61
4	1	0	1	8.93	2.58
5	1	1	0	8.84	3.51
6	0	1	1	8.76	4.02
7	1	1	8	8.86	5.86
8	8	1	1	8.87	10.37
9	1	8	1	8.82	2.93
10	55	19	26	18.95	8.99

RSSE	RSsum
0	5.730
1	0.000
2	2.260
3	4.610
4	2.580
5	3.510
6	4.020
7	2.135
8	4.574
9	3.661
10	5.192

No	Est	Exp
1	2.135	5.86
2	4.574	10.37
3	3.661	2.93
4	5.192	8.99

QN	X1	X2	X3	L	sqNeff
0	1	1	1	8.70	71.90
1	0	0	1	8.83	114.68
2	0	1	0	8.75	108.70
3	1	0	0	9.00	89.55
4	1	0	1	8.93	103.84
5	1	1	0	8.84	83.79
6	0	1	1	8.76	79.28
7	1	1	8	8.86	59.46
8	8	1	1	8.87	71.24
9	1	8	1	8.82	80.92
10	55	19	26	18.95	63.38

QNE	sqNeff
0	71.900
1	114.680
2	108.700
3	89.550
4	103.840
5	83.790
6	79.280
7	98.554
8	85.744
9	89.591
10	79.123

No	Est	Exp
1	98.554	59.46
2	85.744	71.24
3	89.591	80.92
4	79.123	63.38

RSP	X1	X2	X3	L	RSvQN
0	1	1	1	8.70	31.9
1	0	0	1	8.83	0.0
2	0	1	0	8.75	8.3
3	1	0	0	9.00	20.6
4	1	0	1	8.93	9.9
5	1	1	0	8.84	16.8
6	0	1	1	8.76	20.3
7	1	1	8	8.86	39.4
8	8	1	1	8.87	58.2
9	1	8	1	8.82	14.5
10	55	19	26	18.95	56.7

RSPE	RSvQN
0	31.900
1	0.000
2	8.300
3	20.600
4	9.900
5	16.800
6	20.300
7	11.096
8	21.652
9	17.676
10	27.285

No	Est	Exp
1	11.096	39.4
2	21.652	58.2
3	17.676	14.5
4	27.285	56.7

RRP	X1	X2	X3	L	RSrpr
0	1	1	1	8.70	0.269
1	0	0	1	8.83	0.000
2	0	1	0	8.75	0.000
3	1	0	0	9.00	0.156
4	1	0	1	8.93	0.000
5	1	1	0	8.84	0.063
6	0	1	1	8.76	0.000
7	1	1	8	8.86	0.084
8	8	1	1	8.87	3.236
9	1	8	1	8.82	0.014
10	55	19	26	18.95	1.252

RRPE	RSrpr
0	0.269
1	0.000
2	0.000
3	0.156
4	0.000
5	0.063
6	0.000
7	0.046
8	0.151
9	0.063
10	0.224

No	Est	Exp
1	0.046	0.084
2	0.151	3.236
3	0.063	0.014
4	0.224	1.252

IEnt	X1	X2	X3	L	Entro
0	1	1	1	8.70	4.00
1	0	0	1	8.83	11.61
2	0	1	0	8.75	11.61
3	1	0	0	9.00	8.00
4	1	0	1	8.93	11.61
5	1	1	0	8.84	8.00
6	0	1	1	8.76	11.61
7	1	1	8	8.86	4.00
8	8	1	1	8.87	2.00
9	1	8	1	8.82	11.61
10	55	19	26	18.95	4.75

IEntE	Entro
0	4.000
1	11.610
2	11.610
3	8.000
4	11.610
5	8.000
6	11.610
7	10.371
8	7.338
9	9.360
10	5.203

No	Est	Exp
1	10.371	4.00
2	7.338	2.00
3	9.360	11.61
4	5.203	4.75

IEne	X1	X2	X3	L	Energ
0	1	1	1	8.70	16
1	0	0	1	8.83	0
2	0	1	0	8.75	0
3	1	0	0	9.00	8
4	1	0	1	8.93	0
5	1	1	0	8.84	8
6	0	1	1	8.76	0
7	1	1	8	8.86	16
8	8	1	1	8.87	18
9	1	8	1	8.82	0
10	55	19	26	18.95	14

IEneE	Energ
0	16.000
1	0.000
2	0.000
3	8.000
4	0.000
5	8.000
6	0.000
7	2.560
8	9.280
9	4.800
10	13.565

No	Est	Exp
1	2.560	16
2	9.280	18
3	4.800	0
4	13.565	14